Takeda Reports Zasocitinib Achieves High Psoriasis Clearance
Takeda announced Phase 3 results for zasocitinib (TAK-279) at the 2026 AAD meeting showing about 69–71% of patients achieved clear or almost clear skin (sPGA 0/1) at week 16 and significant PASI 75/90/100 improvements versus placebo and apremilast. Safety was consistent with Phase 2b with no new signals, responses deepened through week 24 and remained durable to week 60; Takeda plans NDA submissions starting fiscal 2026.
Scoring Rationale
Strong, well-powered Phase 3 efficacy with official AAD presentation; limited by clinical focus outside core data-science topics.
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Sources
- Read OriginalTakeda’s Zasocitinib Delivered Rapid and Durable Skin Clearance in a Convenient Once-Daily Pill, Affirming Promise to Reshape Psoriasis Caremontrealgazette.com


