Researchinstruction tuningantibody designprotein language modelsllm
AFD-Instruction Advances Antibody Design With Instructions
8.2
Relevance Score
Researchers on arXiv (submitted Feb 4, 2026) present AFD-Instruction, the first large-scale instruction dataset pairing antibody sequences with functional annotations for understanding and design. The dataset contains antibody understanding (inferring function from sequences) and antibody design (de novo sequence generation under functional constraints) and shows that instruction-tuning general LLMs improves performance across diverse antibody tasks. This links sequences to textual function descriptions, aiding therapeutic modeling.
